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Mesothelioma and Non Asbestos ExposureThe majority of mesothelioma cases occur on the linings of the lungs and abdomen. This rare cancer may develop in the linings around the heart or testes (pericardium).Asbestos is a major mesothelioma-related risk factor. Some patients with mesothelioma do not have a previous history of asbestos exposure.Exposure to AsbestosAsbestos is a natural mineral that was previously used in industrial and construction products across the globe. People who worked in asbestos-related industries handled the substance on a daily basis which put them at risk of exposure. Asbestos fibers can become trapped in the lungs, which can lead to progressive lung disease. This is called asbestosis. Over time the fibers that are trapped can also lead to mesothelioma. Asbestos fibers can be breathed in, eaten or absorbed through the skin. The risk of developing mesothelioma or other asbestos-related illnesses increases when exposed.The majority of mesothelioma cases result from occupational exposure. Asbestos was used in various trades, such as construction, insulation and electrical work, as well as automobile maintenance and pipefitting. These trades are typically heavily populated by males, and as a result, male mesothelioma cases comprise 75-80% of all reported cases. However, the phasing out of asbestos in the United States and other first-world countries has reduced exposure to asbestos on the job. This has caused a shift in cases, with occupational exposure becoming more common.Non-occupational mesothelioma can develop when asbestos is released from the workplace environment or found in the school or home surroundings. It can also be caused by secondhand exposure, such as when a family member is exposed to the work clothes of an asbestos-working worker. The people who suffer from this type of exposure may experience symptoms such as shortness of breath or chest pain that is commonly mistaken for heart or lung conditions.Some studies have linked mesothelioma with non-occupational exposure, however the results are different. The studies were conducted with a small number of participants, and the degree of heterogeneity between studies was quite high. It is imperative to conduct further studies to confirm the connection between non-occupational asbestos exposure and mesothelioma.People who have been exposed to non-occupational asbestos should discuss their asbestos history with their physician. They should seek mesothelioma tests when they are concerned and request the referral to an expert. Specialists in mesothelioma will provide the best treatment and care to improve a patient’s outlook. They will review medical records and perform imaging tests to determine if mesothelioma is present. They will also offer advice on how to file a mesothelioma lawsuit to receive compensation from an asbestos trust fund.Secondhand ExposureWhile asbestos exposure is the primary cause of mesothelioma not the only way to get this cancer. There is some evidence that people who haven’t handled asbestos or worked in industries that have asbestos-related activities may still develop mesothelioma. This is referred to as secondary asbestos exposure, or non-occupational asbestos exposure.Asbestos fibers are small and are able to stick to clothing, hair and skin. In the end, workers can bring the dangerous fibers home in their work clothes and transfer them to family members. The asbestos fibers can cause mesothelioma when they are inhaled or consumed.This type of mesothelioma occurs more often in women and is usually found in the lung. It can also affect the chest wall or abdomen. A shortness of breath is the most common sign. It can be accompanied by a variety of other symptoms, including fluid in the lungs and swelling in the scrotum.The mesothelioma which occurs in the lungs is called mesothelioma pleural. Mesothelioma affecting the stomach or chest wall is known as mesothelioma of the peritoneal region. People suffering from this kind of mesothelioma can experience a variety of symptoms such as abdominal pain, breathing problems and constipation.columbus asbestos attorneys have reported that people with no history of occupational exposure to asbestos can still develop mesothelioma as a result of exposure to asbestos through secondhand fibers. The people who were affected typically resided with someone who was exposed to asbestos. They could have handled the worker’s clothing, or they might have been in contact with asbestos in other ways.Veterans are at a high risk of developing mesothelioma due to the extensive asbestos used in military bases, vessels and vehicles. The Navy is especially at risk due to asbestos being used to protect the hull of the ship as well as to protect gun turrets. Asbestos was also often brought home by sailors from their duties aboard ships that had been infected with asbestos.Environmental ExposureMesothelioma has been linked to a variety of materials. The disease is often associated with asbestos exposure. Asbestos is a mineral that occurs naturally that was used for a variety of years in manufacturing. The mineral is heat-resistant and strong making it ideal for insulation, brakes and flooring, shingles and many other products. Asbestos is broken down to dust which can be breathed in and swallowed. These fibers may remain in the stomach or lungs for a long time, triggering mesothelioma-related symptoms.The most common mesothelioma symptoms are breathing difficulties, chest pain and abdominal discomfort. Asbestos exposure can cause these symptoms to last for up to 60 years. It is important to consult a doctor when you experience these symptoms. Telling your doctor about asbestos exposure is essential. This can help avoid a false diagnosis and ensure that you receive the correct treatment.Mesothelioma that is caused by exposure to asbestos is more prevalent in people who work directly with the substance However, it is also able to affect the loved ones of those exposed. This is referred to as secondary exposure. Family members could take in asbestos fibers or swallow them on the clothing of a worker, shoes, or other tools. They could also be exposed to asbestos by someone who brings home the particles on their clothing or hair. This is the reason mesothelioma sufferers and their families must be sure to wash their clothing properly after working around asbestos.There is a huge body of literature showing the connection between asbestos and mesothelioma. However there is no definitive conclusions regarding the role of other agents. There is some evidence that suggests that the zeolites, namely erionite and chlorosotile are able to cause mesothelioma. Erionite is found in the soil and rocks from certain areas in Turkey where the risk of pleural mesothelioma is high.The study of the connection between asbestos and mesothelioma is ongoing. Funnel plots have indicated the potential for bias in publications, and the between-study heterogeneity is high. It is clear that asbestos exposure is the biggest mesothelioma-related risk factor.GeneticsMesothelioma is a rare condition caused by malignant mesothelial cells that develop out of control and invade surrounding tissues. It is also able to spread throughout the body via the lymphatic or blood system, which can affect other organs. Asbestos is the main cause, but it is not the sole cause. The condition may also be triggered by other genetic or environmental factors.In some cases, mesothelioma has occurred in people who had no direct exposure to asbestos. They are known as non-occupational mesothelioma sufferers. They usually had an indirect exposure due to the handling of contaminated clothing or household items by an asbestos-exposed individual in their household. For example, it is possible for someone to be diagnosed with pleural mesothelioma as a result of the exposure to asbestos fibers in clothing belonging to a loved ones. Studies show that this type of mesothelioma tends to have a longer latency period and is more likely to be affecting women than men.Scientists are currently studying the possibility that a genetic predisposition to mesothelioma could play a role in the development of the disease. Recent studies have shown that mutations in BAP1, a gene, increases the risk of mesothelioma among those who are exposed to asbestos. This finding is especially important because it could be the basis for improved screening procedures for those who are at risk of developing mesothelioma.Researchers have discovered that a variety of genes are associated with mesothelioma. Some of these genes are involved in suppressing tumor growth and are often mutated or altered in mesothelioma patients. These genes include large tumor suppressor 2 (LATS2) and NF2.People who have a family history of mesothelioma are at a higher chance of contracting the cancer. This is because some genes, such as BAP1 BAP1 gene, can be passed down from an individual parent. Asbestos was extensively used in the military for a number of years and veterans have the highest mesothelioma rates when compared to other occupational categories. The people who served on ships or in the Navy were at the highest risk due to asbestos exposure in shipbuilding, insulation, and fireproofing materials.